1-Methylpiperidin-4-aMine dihydrochloride
4-Piperidinamine,1-methyl-, hydrochloride (1:2)
CAS: 1193-03-9
Molecular Formula: C6H6BFO2
1-Methylpiperidin-4-aMine dihydrochloride - Names and Identifiers
1-Methylpiperidin-4-aMine dihydrochloride - Physico-chemical Properties
| Molecular Formula | C6H6BFO2 |
| Molar Mass | 139.92 |
| Melting Point | 101-110°C(lit.) |
| Boling Point | 57～60℃/12mm |
| Storage Condition | Room Temprature |
1-Methylpiperidin-4-aMine dihydrochloride - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
1-Methylpiperidin-4-aMine dihydrochloride - Introduction
4-Amino-1-methylpiperidine dihydrochloride, also known as 1-methyl-4-piperazine dihydrochloride, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder.
-Formula: C6H10N3 · 2HCl.
-Molecular weight: 209.19.
-Melting point: about 153-155 degrees Celsius.
-Solubility: The dihydrochloride salt is soluble in water and many organic solvents. It is stable at room temperature.
Use:
4-amino -1-methyl piperidine dihydrochloride has a wide range of applications in the pharmaceutical industry, mainly used in the following areas:
-Neuroscience Research: Used as an inhibitor of the gamma amine transporter (GAT-1) that selectively blocks the norepinephrine transporter in the brain.
-Tumor treatment research: used to develop and research new anti-tumor drugs against tumor cells.
-Dissociation and ion exchange: used for the synthesis of cation exchange resins or as biological separation reagents.
Preparation Method:
The preparation of 4-amino-1-methylpiperidine dihydrochloride is mainly carried out by the following steps:
1. Dissolve 4-amino -1-methyl piperidine in hydrochloric acid.
2. Cool the solution and crystallize the product.
3. Filtration and washing to give the pure dihydrochloride product.
4. Dry the product and store.
Safety Information:
-4-Amino-1-methylpiperidine dihydrochloride is a relatively safe compound, but the following precautions are still needed:
-Use appropriate personal protective equipment such as lab gloves and eye/face protection when exposed.
-Avoid inhalation of powder or contact with skin. Ventilate when necessary and observe good laboratory safety practices during operation.
-Store in a dry, cool, ventilated place.
-Avoid contact with substances such as strong oxidants and acids to prevent dangerous reactions.
-When using and handling the compound, follow the recommendations of the relevant safety data sheet. In case of discomfort or unclear conditions, professional medical or toxicology counseling should be sought.
Nature:
-Appearance: White crystalline powder.
-Formula: C6H10N3 · 2HCl.
-Molecular weight: 209.19.
-Melting point: about 153-155 degrees Celsius.
-Solubility: The dihydrochloride salt is soluble in water and many organic solvents. It is stable at room temperature.
Use:
4-amino -1-methyl piperidine dihydrochloride has a wide range of applications in the pharmaceutical industry, mainly used in the following areas:
-Neuroscience Research: Used as an inhibitor of the gamma amine transporter (GAT-1) that selectively blocks the norepinephrine transporter in the brain.
-Tumor treatment research: used to develop and research new anti-tumor drugs against tumor cells.
-Dissociation and ion exchange: used for the synthesis of cation exchange resins or as biological separation reagents.
Preparation Method:
The preparation of 4-amino-1-methylpiperidine dihydrochloride is mainly carried out by the following steps:
1. Dissolve 4-amino -1-methyl piperidine in hydrochloric acid.
2. Cool the solution and crystallize the product.
3. Filtration and washing to give the pure dihydrochloride product.
4. Dry the product and store.
Safety Information:
-4-Amino-1-methylpiperidine dihydrochloride is a relatively safe compound, but the following precautions are still needed:
-Use appropriate personal protective equipment such as lab gloves and eye/face protection when exposed.
-Avoid inhalation of powder or contact with skin. Ventilate when necessary and observe good laboratory safety practices during operation.
-Store in a dry, cool, ventilated place.
-Avoid contact with substances such as strong oxidants and acids to prevent dangerous reactions.
-When using and handling the compound, follow the recommendations of the relevant safety data sheet. In case of discomfort or unclear conditions, professional medical or toxicology counseling should be sought.
Last Update：2024-04-09 15:17:51
